Youth serum injections in Istanbul

For dull or dehydrated skin on the face, décolletage or hands. This page explains what is in the serum, how a course works, what is and is not proven, and how it differs from PRP.

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  • Treatment time Depends on the areas treated; ask at consultation
  • Hospital stay None: you go home the same day
  • Time in Istanbul Short stay per session; a course needs repeat visits
  • Back to work Straight away for most people
Illustrative artwork. Not a patient or treatment result.

What are youth serum injections?

Youth serum injections place a ready-made serum of hyaluronic acid, peptides, amino acids and vitamins into the skin over a course of sessions, much like mesotherapy. The aim is better hydration, elasticity and glow on the face, décolletage and hands. The Turkish name, gençlik aşısı, translates as 'youth vaccine', but this is not a vaccine, and it is not PRP: nothing is taken from your blood. Most people have 1–5 sessions, 1–3 weeks apart, and go straight back to daily life. Independent evidence for multi-ingredient cocktails like this is limited.

What it can do

  • Aim to improve hydration, elasticity and glow
  • Treat the face, décolletage and hands
  • Fit around daily life, usually with no downtime

What it cannot do

  • Stop or reverse ageing
  • Lift sagging skin or add volume like a filler
  • Relax expression lines as anti-wrinkle injections do
  • Offer proven long-term results: independent data are lacking

Is it right for you?

Suitability is confirmed at an in-person examination of your skin's elasticity, lines, tendency to sag and hydration.

Usually a good fit if

  • Dull or dehydrated skin on the face, décolletage or hands
  • Young, middle-aged or more weathered skin
  • Wanting little or no downtime
  • Comfortable that evidence is limited and results vary

Better to wait or consider alternatives if

  • Pregnancy, breastfeeding, cancer, diabetes or urticaria (excluded for similar mesotherapy)
  • Allergy to any ingredient in the serum
  • An active infection in the treatment area
  • Hoping for a lift or added volume

Techniques

'Youth injection' is used loosely for quite different treatments. This page covers only the first below.

Youth serum (this treatment)

A ready-made serum of hyaluronic acid, peptides, amino acids and vitamins, given as micro-injections over a course.

Best for

Hydration and glow over a course

PRP (platelet-rich plasma)

Your own blood is spun to concentrate platelets, then injected or applied with microneedling. Evidence for rejuvenation is limited. It is a different treatment, not the one described here.

Best for

Comparison only

Classic mesotherapy

A personal mix chosen after examination rather than one formula; see mesotherapy.

Best for

When a personal mix is preferred

Op. Dr. Bilgehan İlker

Op. Dr. Bilgehan İlker

Specialist in plastic, reconstructive and aesthetic surgery

  • Specialist training: Dokuz Eylül University
  • Medical degree: Trakya University
  • Health tourism authorization: ST-2657
  • Dr. İlker speaks English and Turkish.
Dr. Bilgehan İlker

How Dr. İlker approaches youth serum injections

Op. Dr. Bilgehan İlker is a specialist in plastic, reconstructive and aesthetic surgery, trained at Dokuz Eylül University. She describes this serum as one she particularly likes to use for the face, décolletage and hands, and says plainly that it does not stop ageing.

Her serum is known as H-100; its maker and registration could not be independently confirmed, so ask to see the product and its label.

  • Sessions set by your skin Elasticity, lines, tendency to sag and hydration decide the number and spacing of sessions.
  • Spacing by skin type Every 2–3 weeks for young or middle-aged skin, 1–2 weeks for weathered skin; on average 1–5 sessions.
  • No claims from the label The effect is judged on your skin, not the ingredient list.

The treatment, step by step

A session is a short clinic visit.

  1. Assessment

    Elasticity, lines, tendency to sag and hydration are assessed to plan the course.

  2. Cleansing

    The skin is cleaned and disinfected; sterile, single-use material is used.

  3. Injections

    The serum is injected into the skin of the agreed areas.

  4. Aftercare advice

    You receive instructions for the rest of the day and your next date.

  5. The course

    Sessions repeat every 1–3 weeks, on average 1–5 in total.

Your days in Istanbul

No hospital stay; sessions 1–3 weeks apart mean travelling patients plan repeat visits.

  1. Examination

    Before your first session

    Arrive in time for an in-person examination.

  2. Short visit

    Treatment day

    Injections, then your usual day; follow the aftercare you are given.

  3. Next steps

    Before you fly home

    Agree the next session and which signs to report.

Recovery, day by day

This is the typical pattern; yours may differ.

  1. Straight after

    Small marks

    Brief redness at injection points; sometimes small bruises.

  2. Hours 0–24

    Daily life

    Most people resume their routine. Follow your instructions; for similar mesotherapy they are to keep the area dry, rest and skip make-up.

  3. Days 2–3

    Watch for infection

    Increasing redness, painful swelling or discharge needs prompt attention.

  4. Weeks 1–3

    Next session

    Due after 1–2 weeks for weathered skin, 2–3 weeks for younger skin.

  5. Months 1–2

    Course ends

    A shorter course is complete; longer courses continue.

  6. After the course

    Review

    The change in your skin is reviewed together before any further sessions.

  7. Later

    Maintenance

    No independent data show how long effects last.

Contact us straight away if you notice

  • Fever, or discharge from injection points
  • Painful lumps that grow, even weeks later
  • Widespread hives, facial swelling or difficulty breathing
  • Severe pain, a white, grey or blue patch near an injection point, or any change in vision

In an emergency, call your local emergency number.

Aftercare at home

  • Follow the written instructions you are given
  • Keep the treated area dry for as long as advised
  • Skip make-up on treated skin until told otherwise
  • Avoid strenuous effort for the rest of the day
  • Report lumps, discharge or fever promptly, even weeks later

Risks and how they are reduced

Side effects are usually minor, but every injection carries risks and the benefit here is uncertain.

Risk is reduced by an examination first, a product you can see, sterile single-use equipment and clear advice on late warning signs.

Risks and how they are reduced
RiskHow often

Redness, tenderness and bruising

Usual at injection points; they settle on their own.

Common

Infection

Outbreaks have followed multi-injection treatments with poorly cleaned equipment.

Rare

Allergic reaction

Any of the many ingredients could cause a reaction; there are no published data for this serum.

Varies

Uncertain benefit

A controlled study of a similar vitamin and hyaluronic acid mixture found no significant benefit.

Varies

Product quality

Counterfeit and unapproved injectables exist; seeing the original packaging is a sensible check.

Varies

Results and how long they last

The aim is better elasticity, hydration and glow, judged once the course is complete.

We found no published clinical study of this serum, and a controlled study of a similar vitamin and hyaluronic acid mixture showed no significant benefit. Results vary from person to person.

How long it lasts: There is no independent data on how long effects last; maintenance is planned individually.

With any surgical or interventional procedure, results vary from person to person. We recommend a detailed consultation with your doctor before any procedure.

Questions to ask at your consultation

Take these to any surgeon you see — including us.

  1. Which product will you use, who makes it, and can I see the label?
  2. What is your specialist training, and who gives the injections?
  3. How many sessions do you suggest, and how far apart?
  4. What evidence supports this serum for my concern?
  5. Is this PRP, mesotherapy or something else?
  6. Whom do I contact with concerns after I fly home?

What shapes your plan and quote

Prices are not published. After assessment you receive a personal written plan stating what is included.

  • The number of sessions
  • The areas treated: face, décolletage or hands
  • Whether other treatments are combined
  • How many visits to Istanbul you need

We do not publish prices: every plan is personal and is written for you after your assessment.

Frequently asked questions

What are youth serum injections?

Injections of a ready-made serum of hyaluronic acid, peptides, amino acids and vitamins, given into the skin over a course. Op. Dr. Bilgehan İlker uses them on the face, décolletage and hands for hydration, elasticity and glow. Despite the Turkish name, 'youth vaccine', it is not a vaccine.

Is it the same as PRP?

No. PRP (platelet-rich plasma) is prepared from your own blood, spun to concentrate platelets and then injected. Youth serum injections use a ready-made product, and no blood is taken. The American Academy of Dermatology notes that evidence for PRP in skin rejuvenation is limited.

What is in the serum?

According to Dr. İlker: hyaluronic acid (100 mg per 5 ml), pro-collagen peptide, mannitol, DMAE, organic silica, several amino acids, hexapeptide-8, pentapeptide-18 and vitamins B1 and B6. Some of these peptides are familiar from skincare creams, but we found no clinical evidence on injecting them.

How many sessions will I need?

On average 1–5. Dr. İlker spaces sessions 2–3 weeks apart for young and middle-aged skin and 1–2 weeks apart for more weathered skin. The exact number depends on your skin's elasticity, lines, tendency to sag and hydration, assessed at examination.

How long do the effects last?

There is no independent data on how long the effects of this serum last. Your skin keeps ageing, and Dr. İlker is clear that the treatment does not stop it. Whether and when to repeat sessions is decided after reviewing your result.

Can I go back to work afterwards?

Yes. Most people return to their usual day straight away; Dr. İlker describes no interruption to social life. You may have small red marks or bruises at the injection points, so follow the aftercare you are given for the rest of the day.

Are there side effects?

Brief redness, tenderness and small bruises are common and settle on their own. Rarely, injections into the skin cause infection, and an allergy to any ingredient is possible. Report fever, discharge or growing painful lumps, and get urgent help for breathing difficulty or widespread hives.

Who should not have it?

There is no published list for this serum. For similar mesotherapy, Dr. İlker does not treat during pregnancy or breastfeeding, or people with cancer, diabetes or urticaria. An ingredient allergy or an infection in the area is also a reason to avoid it.

Youth serum or skin booster?

They are different products. The skin booster Dr. İlker uses is hyaluronic acid with trehalose, injected at six points without adding volume. Youth serum is a multi-ingredient cocktail given as many small injections. Your skin's needs decide which, if either, suits you.

How long should I stay in Istanbul?

One session needs a short stay: there is no hospital stay and most people have no downtime. Plan time for the examination first. Because sessions are 1–3 weeks apart, completing a course means repeat visits, so agree the dates before booking flights.

Medical informationThe information on this page is general information only. It is not medical advice and does not replace a diagnosis or treatment. Every surgical and interventional procedure carries risks, which will be explained to you in detail during your consultation. Whether this procedure suits you can only be decided after an in-person examination and assessment. We encourage you to also seek independent advice from your own doctor before deciding.

Written by the Bilgehan Clinic editorial team from the sources below. Medical review by Op. Dr. Bilgehan İlker is in progress.

Last updated:

A conversation, at your pace.

Would you like an honest view on whether this suits your skin?

Send your questions and Op. Dr. Bilgehan İlker will explain what the serum can and cannot do for you. We also suggest talking to your own doctor before deciding.

Op. Dr. Bilgehan İlker Specialist in plastic, reconstructive and aesthetic surgery
  • Nef 22 Ataköy, D Blok, Kat 1, Daire 36, Çobançeşme E-5 Yanyol Cad. No:22, Bakırköy / İstanbul
  • Monday to Saturday, 10:00–18:00
  • +90 542 280 27 51
  • Dr. İlker speaks English and Turkish.

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How should we reply?

This exchange does not replace a medical examination or diagnosis. Whether a procedure suits you is decided at an in-person examination.

Ask Dr. İlker

Tell us what you are considering. The team replies with next steps and, where it helps, questions from Dr. İlker.

Dr. İlker speaks English and Turkish.

Op. Dr. Bilgehan İlker Specialist in plastic, reconstructive and aesthetic surgery

Let’s plan your consultation

Choose your country code on the left. Enter your number without the country code.

Country

How should we reply?

This exchange does not replace a medical examination or diagnosis. Whether a procedure suits you is decided at an in-person examination.

A question before you decide?

Many people find it easier to decide after a short, honest answer. Ask anything about your procedure; there is no obligation.

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