Anti-wrinkle injections in Istanbul

For frown lines, forehead lines and crow's feet caused by expression: how the injections work, when you see a change, how long it lasts and the side effects to know about.

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  • Treatment time Usually under 15 minutes
  • Hospital stay None — you go home the same day
  • Time in Istanbul One to two days, including your consultation
  • Back to work Straight away for most people
Illustrative artwork. Not a patient or treatment result.

What are anti-wrinkle injections?

Anti-wrinkle injections use tiny doses of botulinum toxin type A to relax the muscles that crease the skin when you frown, raise your brows or smile, softening lines between the brows, across the forehead and around the eyes. A session usually takes under 15 minutes with a very fine needle, normally without anaesthetic, and you can go straight back to your day. The effect is complete at 10–14 days and typically lasts 3–4 months, sometimes longer.

What it can do

  • Soften lines that form when you frown, raise your brows or smile
  • Give a rested look while your face still moves
  • Reduce heavy underarm sweating, an approved medical use

What it cannot do

  • Replace lost volume; that is the role of dermal fillers
  • Erase lines visible at rest or lift loose skin
  • Last for good: treatment has to be repeated

Is it right for you?

They treat lines caused by muscle movement, and the change is subtle and temporary.

Usually a good fit if

  • Frown lines, forehead lines or crow's feet deepen with expression
  • You are 18 or over and in good general health
  • You want softer lines but natural expression
  • You are happy to repeat treatment every few months

Better to wait or consider alternatives if

  • You are pregnant or breastfeeding
  • You have a neuromuscular condition such as myasthenia gravis
  • You have a skin infection in the area, or have reacted to botulinum toxin before
  • Deep lines at rest or low, heavy brows are the main concern; a brow lift may help more
  • You feel pressured into treatment or hope for a dramatic change

Techniques

The medicine is the same; placement and dose change. Brands are dosed in units that cannot be swapped one-for-one.

Upper-face lines

Small amounts go into the frown muscles, the forehead and the muscles at the outer corners of the eyes. The injection points follow the way your own muscles move.

Best for

Frown lines, forehead lines and crow's feet

Underarm sweating

Armpit injections reduce sweating, an approved medical use, and one treatment can bring relief for up to six months. Palms and soles are not covered by the label.

Best for

Heavy underarm sweating

Op. Dr. Bilgehan İlker

Op. Dr. Bilgehan İlker

Specialist in plastic, reconstructive and aesthetic surgery

  • Specialist training: Dokuz Eylül University
  • Medical degree: Trakya University
  • Health tourism authorization: ST-2657
  • Dr. İlker speaks English and Turkish.
Dr. Bilgehan İlker

How Dr. İlker approaches anti-wrinkle injections

Op. Dr. Bilgehan İlker is a specialist in plastic, reconstructive and aesthetic surgery, trained at Dokuz Eylül University. Her own writing stresses that these injections belong with a trained specialist, because dose and placement decide whether a face looks rested or artificial.

Her pages name these injections, with laser skin rejuvenation and RF microneedling, as her three main tools for lines.

  • Assessment first Your face is examined at rest and in motion, with your health and medicines.
  • Only where needed The effect is local, so your plan lists exactly which areas are treated.
  • Written consent Timing and side effects are explained before you agree to treatment.

The treatment, step by step

A typical appointment:

  1. Consultation

    Op. Dr. Bilgehan İlker asks which lines bother you, reviews your health and watches how your face moves.

  2. Photographs and plan

    Photographs are taken and the injection points are planned.

  3. Comfort

    Anaesthetic is not usually needed; numbing cream or ice is available.

  4. Injections

    A very fine needle places small amounts into each target muscle, usually in under 15 minutes.

  5. Back to your day

    You leave straight away, without rubbing the treated areas.

Your days in Istanbul

A short visit is enough; the result develops after you are home.

  1. Consultation in person

    Before your treatment

    Arrive early enough for an unhurried examination; treatment follows once you agree the plan and sign consent.

  2. A short appointment

    Treatment day

    Stay upright for 3–4 hours and leave strenuous exercise for 24 hours.

  3. Know the warning signs

    Before you fly home

    Make sure you know whom to contact about drooping, double vision or difficulty swallowing.

Recovery, day by day

No downtime; the effect develops over about two weeks.

  1. Hours 0–4

    Small marks

    Tiny bumps or redness are normal. Stay upright and do not rub or massage the areas.

  2. Hours 4–24

    Gentle for the day

    No pressing for 12 hours or strenuous exercise for 24; make-up can go on gently.

  3. Days 2–3

    First change

    Softening often begins. A bruise can take about a week to fade.

  4. Days 4–7

    Building up

    The effect keeps increasing.

  5. Days 10–14

    Full effect

    Judge the result now and report any unevenness.

  6. Month 1

    Settled

    A heavy brow or eyelid, if it occurs, shows by now and is temporary.

  7. Months 3–4

    Movement returns

    Lines gradually return. Treatment can be repeated after three months or more.

Contact us straight away if you notice

  • Difficulty swallowing, speaking or breathing (seek emergency care)
  • Double or blurred vision
  • Weakness or numbness away from the treated area
  • An eyelid or brow drooping enough to affect your sight; do not drive

In an emergency, call your local emergency number.

Aftercare at home

  • No rubbing, pressing or massage of the areas for 12 hours.
  • Stay upright for 3–4 hours.
  • No strenuous exercise for 24 hours.
  • Apply make-up gently, without pressing.
  • Note the date and product, and tell anyone treating you in the next four months.

Risks and how they are reduced

Most side effects are mild and short-lived; a few are rare but serious.

A medical assessment, a licensed and traceable product and small, precise doses lower the risks. Counterfeit products used outside medical settings have caused botulism-like illness.

Risks and how they are reduced
RiskHow often

Bruising, redness and swelling

Small marks at the injection points; a bruise can take a week to fade.

Common

Headache

Reported by about 9 in 100 people treated for forehead lines in clinical trials; usually mild.

Common

Drooping eyelid or heavy brow

It can happen if the medicine reaches a nearby muscle; trials reported it in 2–3 in 100 people. It is temporary.

Common

Spread of the effect

The label warns that spread can cause swallowing or breathing problems hours to weeks later. At cosmetic doses this is very unlikely.

Rare

Heart-related events

Rare reports, some fatal, appear in the product information. Mention any heart condition.

Rare

Results and how long they last

The effect builds over two weeks. Lines that form with expression soften most; lines at rest may only partly improve. Your face should still move.

Movement returns gradually, and with repeat treatments some people find the effect lasts longer.

How long it lasts: Typically 3–4 months, sometimes longer; up to six months for underarm sweating.

With any surgical or interventional procedure, results vary from person to person. We recommend a detailed consultation with your doctor before any procedure.

Questions to ask at your consultation

Take these to any surgeon you see — including us.

  1. Who will inject me, and what is their training?
  2. Which product will you use, and will it be recorded?
  3. Which areas do you suggest?
  4. Which side effects need urgent attention, and how do I reach you?
  5. How will the final result be reviewed?
  6. Is my intended use licensed or off-label?

What shapes your plan and quote

Prices are not published. Your written plan, given after assessment, lists the areas and what is included.

  • The number of areas treated
  • The product and the dose you need
  • Medical uses, such as sweating
  • Other treatments at the same visit

We do not publish prices: every plan is personal and is written for you after your assessment.

Frequently asked questions

How long do anti-wrinkle injections last?

Typically 3–4 months, sometimes longer. Muscle movement returns gradually and the lines come back with it, though some people find the effect lasts longer after several treatments. Repeating it more often than every three months has not been studied, so plan intervals at least that long.

How long do they take to work?

The label describes the effect starting within one to two days and building through the first week; most people notice it within 3–7 days. The full result shows at 10–14 days, so judge the outcome after two weeks rather than before.

When can I lie down or exercise afterwards?

Stay upright for 3–4 hours, avoid pressing on the treated areas for 12 hours and leave strenuous exercise for 24 hours. Above all, do not rub or massage the areas, so that the medicine stays exactly where it was placed.

Do the injections hurt?

A very fine needle is used and treatment usually takes under 15 minutes, so anaesthetic is not normally needed. If you are sensitive to needles, numbing cream or ice can be applied first. How it feels varies from person to person.

What side effects can occur?

Redness, swelling or bruising at the injection points are the most common; a bruise can take a week to fade. In clinical trials, headache affected about 9 in 100 people treated for forehead lines, and a temporary heavy brow or drooping eyelid 2–3 in 100.

Will my face look frozen?

It should not. Op. Dr. Bilgehan İlker aims to relax only the muscles behind the lines that bother you, so your face still moves. The dose and the exact injection points decide how natural the result looks, so both are planned around your own expressions.

Can I have them while pregnant or breastfeeding?

It is not recommended. There is no human data on pregnancy or breastfeeding, and animal studies showed effects on growth before birth. Most doctors advise waiting until breastfeeding has finished. Tell Dr. İlker if you are pregnant or trying to conceive.

Can these injections help with teeth clenching?

Injections into the large chewing muscle (masseter) are used for clenching and to slim a broad lower face. This use is off-label, meaning it is not covered by the product licence, and it is not a cure for clenching. Suitability is decided at examination.

Are all anti-wrinkle injections the same product?

No. Several licensed brands of botulinum toxin type A exist, the best known being Botox. Their doses are measured in units that cannot be swapped one-for-one between products, so your record should state exactly which product was used and how much.

Can I have them on a short trip to Istanbul?

Yes. The appointment is short and there is no recovery period, so it fits a brief stay after a proper consultation. The full effect appears at 10–14 days, usually once you are home, so agree before leaving how any questions will be handled.

Medical informationThe information on this page is general information only. It is not medical advice and does not replace a diagnosis or treatment. Every surgical and interventional procedure carries risks, which will be explained to you in detail during your consultation. Whether this procedure suits you can only be decided after an in-person examination and assessment. We encourage you to also seek independent advice from your own doctor before deciding.

Written by the Bilgehan Clinic editorial team from the sources below. Medical review by Op. Dr. Bilgehan İlker is in progress.

Last updated:

A conversation, at your pace.

Would these injections suit you?

Tell us which lines bother you. Op. Dr. Bilgehan İlker will explain whether injections, another treatment or nothing at all makes sense.

Op. Dr. Bilgehan İlker Specialist in plastic, reconstructive and aesthetic surgery
  • Nef 22 Ataköy, D Blok, Kat 1, Daire 36, Çobançeşme E-5 Yanyol Cad. No:22, Bakırköy / İstanbul
  • Monday to Saturday, 10:00–18:00
  • +90 542 280 27 51
  • Dr. İlker speaks English and Turkish.

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How should we reply?

This exchange does not replace a medical examination or diagnosis. Whether a procedure suits you is decided at an in-person examination.

Ask Dr. İlker

Tell us what you are considering. The team replies with next steps and, where it helps, questions from Dr. İlker.

Dr. İlker speaks English and Turkish.

Op. Dr. Bilgehan İlker Specialist in plastic, reconstructive and aesthetic surgery

Let’s plan your consultation

Choose your country code on the left. Enter your number without the country code.

Country

How should we reply?

This exchange does not replace a medical examination or diagnosis. Whether a procedure suits you is decided at an in-person examination.

A question before you decide?

Many people find it easier to decide after a short, honest answer. Ask anything about your procedure; there is no obligation.

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